NARCAN
Destruction
Lifetime of Narcan
The lifetime of Narcan depends on the way it enters the body and the person overall. If taken intravenously, it can take 2 minutes to see effects, while taking it via muscle injection and nasal spray will take 5 minutes and 2-5 minutes respectively. On average, the drug lasts anywhere from a half an hour to an hour long. For some, multiple dosages are required to see effects, as the drug can be ineffective depending on how the effective the opioid was for them.
The half life of Narcan varies based on the age of the patient. For instance, the average 1/2 life of an adult ranges from 30 to 81 minutes as Narcan metabolizes fully into the liver. Infants and young kids can see up to a 3 hour half life. If no opioids are activated in the body, Narcan's effects are negligible.
The half life of Narcan varies based on the age of the patient. For instance, the average 1/2 life of an adult ranges from 30 to 81 minutes as Narcan metabolizes fully into the liver. Infants and young kids can see up to a 3 hour half life. If no opioids are activated in the body, Narcan's effects are negligible.
Oxidation of Narcan
4C19H21NO4 + 93O2 = 4NO2 + 76CO2 + 42H2O
1g C19H21NO4 * (1mol / 327.38g C19H21NO4)
= 0.00305455mol Narcan
0.00305455mol Narcan * (93O2 / 4mol Narcan)
= 0.07101838mol O2
0.07101838mol O2 * (32g O2 / 1mol)
= 2.272g O2 needed for Narcan to completely Oxidize
0.00305455mol Narcan * (4mol NO2 / 4mol Narcan)
= 0.00305455mol NO2
0.00305455mol NO2 * (46g / 1mol NO2)
= 0.14050949g NO2 produced
0.00305455mol Narcan * (42mol H20 / 4mol Narcan)
= 0.0320728202 mol H2O
0.0320728202 mol H2O * (18.02g / 1mol H2O)
= 0.5779522g H2O produced
0.00305455mol Narcan * (76mol CO2 / 4mol Narcan)
= 0.05803653mol CO2
0.05803653mol CO2 * (44.01g / 1mol CO2)
= 2.55418g CO2 produced
Narcan is broken down in the liver and can typically be excreted via urine or feces. Narcan will be fully eliminated from the system within 2-3 days. The metabolization process revolves around the N and O4 in Narcan to be oxidized, which results in the body having major side effects to health such as: chills, hot flashes, diarrhea, weakness, seizures, and even cardiac arrest. As a result, people who have received Narcan after an overdose spend a few days in the hospital to flush the body of both the drug and Narcan.
1g C19H21NO4 * (1mol / 327.38g C19H21NO4)
= 0.00305455mol Narcan
0.00305455mol Narcan * (93O2 / 4mol Narcan)
= 0.07101838mol O2
0.07101838mol O2 * (32g O2 / 1mol)
= 2.272g O2 needed for Narcan to completely Oxidize
0.00305455mol Narcan * (4mol NO2 / 4mol Narcan)
= 0.00305455mol NO2
0.00305455mol NO2 * (46g / 1mol NO2)
= 0.14050949g NO2 produced
0.00305455mol Narcan * (42mol H20 / 4mol Narcan)
= 0.0320728202 mol H2O
0.0320728202 mol H2O * (18.02g / 1mol H2O)
= 0.5779522g H2O produced
0.00305455mol Narcan * (76mol CO2 / 4mol Narcan)
= 0.05803653mol CO2
0.05803653mol CO2 * (44.01g / 1mol CO2)
= 2.55418g CO2 produced
Narcan is broken down in the liver and can typically be excreted via urine or feces. Narcan will be fully eliminated from the system within 2-3 days. The metabolization process revolves around the N and O4 in Narcan to be oxidized, which results in the body having major side effects to health such as: chills, hot flashes, diarrhea, weakness, seizures, and even cardiac arrest. As a result, people who have received Narcan after an overdose spend a few days in the hospital to flush the body of both the drug and Narcan.